Article
Identification of a novel HLA-A allele, HLA-A*01:195, in a UAE national.
Human immunology - 1 Jul 2016
Abdrabou Wael, Witzel Ini-Isabée, Paduch Agnieszka, Tay Guan, Alsafar Habiba
Abstract excerpt
A novel human leucocyte antigen (HLA)-A allele, HLA-A*01:195, was identified by sequence-based typing (SBT) in a UAE national subject. The novel allele is identical to its closest known allele, HLA-A*01:01:01:01, in exon 2, 3 and 4, except for a single nucleotide mutation of A to G at position 442 in exon 3 (codon 124 in the α2 domain of the α chain of the mature protein). This A to G mutation results in an amino...
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