Article
The Power of Inbreeding: NGS-Based GWAS of Rice Reveals Convergent Evolution during Rice Domestication.
Molecular plant - 6 Jul 2016
Wang Hongru, Xu Xun, Vieira Filipe Garrett, Xiao Yunhua, Li Zhikang, Wang Jun, Nielsen Rasmus, Chu Chengcai
Abstract excerpt
Low-coverage whole-genome sequencing is an effective strategy for genome-wide association studies in humans, due to the availability of large reference panels for genotype imputation. However, it is unclear whether this strategy can be utilized in other species without reference panels. Using simulations, we show that this approach is even more relevant in inbred species such as rice (Oryza sativa L.), which...
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