Article
Prognostic value of DNA repair based stratification of hepatocellular carcinoma.
Scientific reports - 13 May 2016
Lin Zhuo, Xu Shi-Hao, Wang Hai-Qing, Cai Yi-Jing, Ying Li, Song Mei, Wang Yu-Qun, Du Shan-Jie, Shi Ke-Qing, Zhou Meng-Tao
Abstract excerpt
Aberrant activation of DNA repair is frequently associated with tumor progression and response to therapy in hepatocellular carcinoma (HCC). Bioinformatics analyses of HCC data in the Cancer Genome Atlas (TCGA) were performed to define DNA repair based molecular classification that could predict the prognosis of patients with HCC. Furthermore, we tested its predictive performance in 120 independent cases. Four...
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