Article
A Novel Variant in CMAH Is Associated with Blood Type AB in Ragdoll Cats.
PloS one - 1 Jan 2016
Gandolfi Barbara, Grahn Robert A, Gustafson Nicholas A, Proverbio Daniela, Spada Eva, Adhikari Badri, Cheng Janling, Andrews Gordon, Lyons Leslie A, Helps Chris R
Abstract excerpt
The enzyme cytidine monophospho-N-acetylneuraminic acid hydroxylase is associated with the production of sialic acids on cat red blood cells. The cat has one major blood group with three serotypes; the most common blood type A being dominant to type B. A third rare blood type is known as AB and has an unclear mode of inheritance. Cat blood type antigens are defined, with N-glycolylneuraminic acid being associated...
Topics
- ABO Blood-Group System
- Animals
- Cats
- DNA, Complementary
- Exons
- Gene Frequency
- Genome
- Genome-Wide Association Study
- Genotype
- Mixed Function Oxygenases
- Models, Molecular