Article
The platelet derived growth factor-B polymorphism is associated with risk of severe fever with thrombocytopenia syndrome in Chinese individuals.
Oncotarget - 31 May 2016
Zhang Xiao-Ai, Guo Chen-Tao, Lu Qing-Bin, Hu Jian-Gong, Cui Ning, Yang Zhen-Dong, Peng Wei, Liu Rong, Hu Chun-Yan, Qin Shu-Li, Wang Xian-Jun, Ding Shu-Jun, Huang Dou-Dou, Liu Wei, Cao Wu-Chun
Abstract excerpt
BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel bunyavirus named SFTS virus (SFTSV). We hypothesize that host genetic variations may contribute to susceptibility to SFTS. RESULTS: Compared with the rs1800818 AA genotype, AG + GG genotypes were significantly associated with increased susceptibility to SFTS (odds ratio, 1.66, 95% confidence interval...
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