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Article

ARID1A alteration in aggressive urothelial carcinoma and variants of urothelial carcinoma.

Human pathology - 1 Sept 2016

Li Jianhong, Lu Shaolei, Lombardo Kara, Monahan Rene, Amin Ali

Abstract excerpt

ARID1A mutation leads to loss of the products of this tumor-suppressor gene. Studies demonstrated ARID1A mutation in 20% of stage IV urothelial carcinomas (UCs) with worse prognosis. The expression of ARID1A in aggressive variants of UC is not studied properly. From 2000 to 2015, 81 variants of UC (29 micropapillary, 33 sarcomatoid, 31 small cell, 2 nested, and 3 plasmacytoid variants) were identified in the...

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PMID: 27137986
DOI: 10.1016/j.humpath.2016.04.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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