Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A variant allele of the Mediterranean-fever gene increases the severity of gout.

International journal of rheumatic diseases - 1 Jan 2018

Balkarli Ayse, Tepeli Emre, Balkarli Huseyin, Kaya Arif, Cobankara Veli

Abstract excerpt

BACKGROUND: Gout is a clinical syndrome that occurs as an inflammatory response to increased concentration of uric acid and monosodium urate crystals. Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease with autosomal recessive inheritance. The Mediterranean fever (MEFV) gene is responsible for FMF and encodes pyrin that suppresses the inflammatory response. Most of the FMF-related...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Case-Control Studies
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Risk Factors

Share to Severity of Illness Index

Source

Identifiers

PMID: 27125729
DOI: 10.1111/1756-185X.12872

Genes

MEFV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A variant allele of the Mediterranean-fever gene increases the severity of gout.PMID 27125729Read ↗

Familial Mediterranean Fever Gene Mutations and Gout as an Auto-Inflammatory ArthropathySemantic proximity Read ↗

[Is there a relationship between gouty arthritis and Mediterranean fever gene mutations?].Semantic proximity Read ↗

[Role of genetics in familial Mediterranean fever].Semantic proximity Read ↗

The familial Mediterranean fever gene as a modifier of periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome.Semantic proximity Read ↗

Mutations in the gene for familial Mediterranean fever: do they predispose to inflammation?Semantic proximity Read ↗

The relationship between the MEFV genotype, clinical features, and cytokine-inflammatory activities in patients with familial mediterranean fever.Semantic proximity Read ↗

The clinical effect of gene mutations in familial Mediterranean fever disease.Semantic proximity Read ↗

Prevalence and significance of MEFV gene mutations in patients with gouty arthritis.Semantic proximity Read ↗

The significance of carrying MEFV variants in symptomatic and asymptomatic individuals.Semantic proximity Read ↗

MEFV gene 3'-UTR Alu repeat polymorphisms in patients with familial Mediterranean fever.Semantic proximity Read ↗

The role of Mediterranean fever gene variants in patients with periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndromeSemantic proximity Read ↗

Frequency of MEFV mutation and genotype-phenotype correlation in cases with dysmenorrhea.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.