Article
An international survey of surveillance schemes for unaffected BRCA1 and BRCA2 mutation carriers.
Breast cancer research and treatment - 1 Jun 2016
Madorsky-Feldman Dana, Sklair-Levy Miri, Perri Tamar, Laitman Yael, Paluch-Shimon Shani, Schmutzler Rita, Rhiem Kerstin, Lester Jenny, Karlan Beth Y, Singer Christian F, Van Maerken Tom, Claes Kathleen, Brunet Joan, Izquierdo Angel, Teulé Alex, Lee Jong Won, Kim Sung-Won, Arun Banu, Jakubowska Anna, Lubinski Jan, Tucker Katherine, Poplawski Nicola K, Varesco Liliana, Bonelli Luigina Ada, Buys Saundra S, Mitchell Gillian, Tischkowitz Marc, Gerdes Anne-Marie, Seynaeve Caroline, Robson Mark, Kwong Ava, Tung Nadine, Tessa Nalven, Domchek Susan M, Godwin Andrew K, Rantala Johanna, Arver Brita, Friedman Eitan
Abstract excerpt
Female BRCA1/BRCA2 mutation carriers are at substantially increased risk for developing breast and/or ovarian cancer, and are offered enhanced surveillance including screening from a young age and risk-reducing surgery (RRS)-mastectomy (RRM) and/or salpingo-oophorectomy (RRSO). While there are established guidelines for early detection of breast cancer in high-risk women who have not undergone RRM, there are less...
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