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Cervical Microbiome and Cytokine Profile at Various Stages of Cervical Cancer: A Pilot Study

26 Apr 2016

Abstract excerpt

Cervical cancer (CC) is caused by high-risk human papillomavirus persistence due to the immunosuppressive tumor microenvironment mediated by cytokines. Vaginal microbiota determines the presence of certain cytokines locally. We assessed the association between cervical microbiota diversity and the histopathological diagnosis of each stage of CC, and we evaluated mRNA cervical expression levels of IL-4, IL-6,...

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PMID: 27115350
DOI: 10.1371/journal.pone.0153274

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