Article
Equine Mesenchymal Stromal Cells from Different Sources Efficiently Differentiate into Hepatocyte-Like Cells.
Tissue engineering. Part C, Methods - 1 Jun 2016
Pennington Matthew R, Curtis Theresa M, Divers Thomas J, Wagner Bettina, Ness SallyAnne L, Tennant Bud C, Van de Walle Gerlinde R
Abstract excerpt
Adult equine hepatocytes have proven challenging to culture long term in vitro as they rapidly lose their morphology and functionality, thus limiting studies on liver function and response to disease. In this study, we describe for the first time the differentiation of equine mesenchymal stromal cells (MSC) from a variety of sources into functional hepatocyte-like cells (HLC). First, we differentiated equine...
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