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Article

Susceptibility of human tonsillar epithelial cells to enterovirus 71 with normal cytokine response.

Virology - 1 Jul 2016

Xie Guang-Cheng, Guo Ni-Jun, Grénman Reidar, Wang Hong, Wang Ying, Vuorenmma Minna, Zhang Qing, Zhang Shuang, Li Hui-Ying, Pang Li-Li, Li Dan-Di, Jin Miao, Sun Xiao-Man, Kong Xiang-Yu, Duan Zhao-Jun

Abstract excerpt

A recent histopathologic study implicated human tonsillar crypt epithelium as an important site for EV71 replication in EV71-caused fatal cases. This study aimed to confirm the susceptibility of human tonsillar epithelium to EV71. Two human tonsillar epithelial cell lines (UT-SCC-60A and UT-SCC-60B) were susceptive to EV71, and PI3K/AKT, p38, ERK1/2, and JNK1/2 signal pathways were activated. Interferon-α, IL-8,...

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PMID: 27107253
DOI: 10.1016/j.virol.2016.04.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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