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Correlating <i>Flavivirus</i> virulence and levels of intrinsic disorder in shell proteins: protective roles <i>vs.</i> immune evasion

7 Apr 2016

Abstract excerpt

Computational analyses revealed correlations between the intrinsic disorder propensity of shell proteins and case fatality rates (CFRs) among Flaviviruses and within at least two Flavivirus species, such as tick-borne encephalitis virus (TBEV) and dengue virus (DENV). The shell proteins analyzed in this study are capsid (C) and membrane (PrM, Pr, and M) proteins. The highest correlations can be found when...

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PMID: 27102744
DOI: 10.1039/c6mb00228e

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