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Article

Identification of CiaR Regulated Genes That Promote Group B Streptococcal Virulence and Interaction with Brain Endothelial Cells.

PloS one - 1 Jan 2016

Mu Rong, Cutting Andrew S, Del Rosario Yvette, Villarino Nicholas, Stewart Lara, Weston Thomas A, Patras Kathryn A, Doran Kelly S

Abstract excerpt

Group B Streptococcus (GBS) is a major causative agent of neonatal meningitis due to its ability to efficiently cross the blood-brain barrier (BBB) and enter the central nervous system (CNS). It has been demonstrated that GBS can invade human brain microvascular endothelial cells (hBMEC), a primary component of the BBB; however, the mechanism of intracellular survival and trafficking is unclear. We previously...

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Share to Bacterial Adhesion
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelium, Vascular

Share to Fluorescent Antibody Technique

Share to Genes, Regulator

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Source

Open in PubMed Open full text

Identifiers

PMID: 27100296
DOI: 10.1371/journal.pone.0153891
PMCID: PMC4839699

Genes

LAMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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