Article
Local allergic rhinitis: A critical reappraisal from a paediatric perspective.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Sept 2016
Arasi Stefania, Pajno Giovanni Battista, Lau Susanne, Matricardi Paolo Maria
Abstract excerpt
The so-called local allergic rhinitis (LAR) has been proposed as a phenotype of rhinitis with Th2-driven prominent local allergic inflammation, nasal synthesis of specific IgE and a positive response to a nasal allergen provocation test, in the absence of 'systemic' atopy (negative skin prick test and serum allergen-specific IgE antibodies). To date, available data on LAR are mostly focused on adults. The purpose...
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