Article
The haplotype of UBE2L3 gene is associated with Hashimoto's thyroiditis in a Chinese Han population.
BMC endocrine disorders - 19 Apr 2016
Wang Yu, Zhu Yuan-feng, Wang Qiong, Xu Jing, Yan Ni, Xu Jian, Shi Liang-feng, He Shuang-tao, Zhang Jin-an
Abstract excerpt
BACKGROUND: The ubiquitin conjugating enzyme E2L3 (UBE2L3) gene is associated with susceptibility to many autoimmune diseases. The aim of this study was to investigate the association between UBE2L3 gene and autoimmune thyroid diseases (AITDs) and their clinical phenotypes. METHODS: We genotyped five single-nucleotide polymorphisms (SNPs) rs131654, rs5754217, rs2298428, rs140489 and rs5998672 of UBE2L3 gene in...
