Article
MERTK as a novel therapeutic target in head and neck cancer.
Oncotarget - 31 May 2016
von Mässenhausen Anne, Sanders Christine, Thewes Britta, Deng Mario, Queisser Angela, Vogel Wenzel, Kristiansen Glen, Duensing Stefan, Schröck Andreas, Bootz Friedrich, Brossart Peter, Kirfel Jutta, Heasley Lynn, Brägelmann Johannes, Perner Sven
Abstract excerpt
Although head and neck cancer (HNSCC) is the sixth most common tumor entity worldwide therapy options remain limited leading to 5-year survival rates of only 50 %. MERTK is a promising therapeutic target in several tumor entities, however, its role in HNSCC has not been described yet. The aim of our study was to investigate the biological significance of MERTK and to evaluate its potential as a novel therapeutic...
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