Article
Airway Microbiota in Severe Asthma and Relationship to Asthma Severity and Phenotypes.
PloS one - 1 Jan 2016
Zhang Qingling, Cox Michael, Liang Zhike, Brinkmann Folke, Cardenas Paul A, Duff Rachael, Bhavsar Pankaj, Cookson William, Moffatt Miriam, Chung Kian Fan
Abstract excerpt
BACKGROUND: The lower airways harbor a community of bacterial species which is altered in asthma. OBJECTIVES: We examined whether the lower airway microbiota were related to measures of asthma severity. METHODS: We prospectively recruited 26 severe asthma, 18 non-severe asthma and 12 healthy subjects. DNA was extracted from induced sputum and PCR amplification of the V3-V5 region of bacterial 16S rRNA gene was...
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