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Article

An Essential Role for COPI in mRNA Localization to Mitochondria and Mitochondrial Function.

Cell reports - 19 Apr 2016

Zabezhinsky Dmitry, Slobodin Boris, Rapaport Doron, Gerst Jeffrey E

Abstract excerpt

Nuclear-encoded mRNAs encoding mitochondrial proteins (mMPs) can localize directly to the mitochondrial surface, yet how mMPs target mitochondria and whether RNA targeting contributes to protein import into mitochondria and cellular metabolism are unknown. Here, we show that the COPI vesicle coat complex is necessary for mMP localization to mitochondria and mitochondrial function. COPI inactivation leads to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27068463
DOI: 10.1016/j.celrep.2016.03.053

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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