Article
Dengue severity associated with age and a new lineage of dengue virus-type 2 during an outbreak in Rio De Janeiro, Brazil.
Journal of medical virology - 1 Jul 2016
Nunes Priscila Conrado Guerra, Sampaio Simone Alves Faria, da Costa Nieli Rodrigues, de Mendonça Marcos Cesar Lima, Lima Monique da Rocha Queiroz, Araujo Saraiva Eliane M, dos Santos Flávia Barreto, Simões Jaqueline Basto Santos, Gonçalves Bianca de Santis, Nogueira Rita Maria Ribeiro, de Filippis Ana Maria Bispo
Abstract excerpt
Dengue virus-type 2 (DENV-2) caused three outbreaks, in the years 1990, 1998, and 2008, in Rio de Janeiro, Brazil. The 2008 outbreak was the most severe in reported cases, hospitalizations, and deaths. To investigate virological and epidemiological factors that may have contributed to the pathogenic profile of 2008 epidemic, 102 patients sera obtained during the epidemic and inter-epidemic periods of three...
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