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Article

Adolescent behavioral and neural reward sensitivity: a test of the differential susceptibility theory.

Translational psychiatry - 5 Apr 2016

Richards J S, Arias Vásquez A, von Rhein D, van der Meer D, Franke B, Hoekstra P J, Heslenfeld D J, Oosterlaan J, Faraone S V, Buitelaar J K, Hartman C A

Abstract excerpt

Little is known about the causes of individual differences in reward sensitivity. We investigated gene-environment interactions (GxE) on behavioral and neural measures of reward sensitivity, in light of the differential susceptibility theory. This theory states that individuals carrying plasticity gene variants will be more disadvantaged in negative, but more advantaged in positive environments. Reward responses...

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Identifiers

PMID: 27045841
DOI: 10.1038/tp.2016.37
PMCID: PMC4872395

Genes

DRD4
HTT

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