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Article

Bipolar Disorder Type 1 in a 17-Year-Old Girl with Wolfram Syndrome.

Journal of child and adolescent psychopharmacology - 1 Oct 2016

Xavier Jean, Bourvis Nadège, Tanet Antoine, Ramos Tatiana, Perisse Didier, Marey Isabelle, Cohen David, Consoli Angèle

Abstract excerpt

OBJECTIVE: Wolfram syndrome (WS, MIM 222300) is a rare autosomal, recessive neurodegenerative disorder associated with mutations in WFS1, a gene that has been associated with bipolar disorder (BD). WS, characterized by the association of juvenile-onset diabetes mellitus (DM) and bilateral progressive optic atrophy (BPOA), encompasses several other clinical features, including cognitive impairments and psychiatric...

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Source

Identifiers

PMID: 27045389
DOI: 10.1089/cap.2015.0241

Genes

WFS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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