Article
Effect of growth differentiation factor‑9 C447T and G546A polymorphisms on the outcomes of in vitro fertilization.
Molecular medicine reports - 1 May 2016
Serdyńska-Szuster Monika, Jędrzejczak Piotr, Ożegowska Katarzyna Ewa, Hołysz Hanna, Pawelczyk Leszek, Jagodziński Paweł Piotr
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in the growth differentiation factor (GDF)‑9 gene are associated with premature ovarian failure, insufficient ovarian stimulation and a poor in vitro fertilization (IVF) score in women with diminished ovarian reserve. The aim of the present study was to assess the effect of C447T (rs254286) and G546A (rs10491279) SNPs on ovary stimulation response, oocyte quality,...
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