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Article

Impact of Deferring Radiation Therapy in Patients With Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer Who Develop Brain Metastases.

International journal of radiation oncology, biology, physics - 1 Jun 2016

Magnuson William J, Yeung Jacky T, Guillod Paul D, Gettinger Scott N, Yu James B, Chiang Veronica L

Abstract excerpt

PURPOSE: To perform a retrospective analysis of patients with epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma who developed brain metastases (BM) to evaluate our hypothesis that the use of upfront EGFR-tyrosine kinase inhibitors (TKIs), and deferral of radiation therapy (RT), would result in inferior intracranial progression-free survival but similar overall survival (OS). METHODS AND...

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Identifiers

PMID: 27034176
DOI: 10.1016/j.ijrobp.2016.01.037

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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