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Article

[Expression of porforin and granzyme B in familial hemophagocytic lymphohistiocytosis].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2016

Zhou X H, Luo J M, Bin Q, Huang X H

Abstract excerpt

OBJECTIVE: To analyze the correlation between genetic variants of PRF1 and expression level of perforin and granzyme B protein, and further determine the relationship between PRF1 gene variants and cytotoxic T lymphocyte/natural killer (CTL/NK) cell function in famililal hemophagocytic lymphohistiocytosis (FHL2). METHODS: Eight children of FHL2 (P1-P8) after treatment, as well as parents and siblings of P1-P5...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Killer Cells, Natural

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Source

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Identifiers

PMID: 27033761
DOI: 10.3760/cma.j.issn.0253-2727.2016.03.010
PMCID: PMC7342954

Genes

PRF1
FHL2
LYST
STX11
STXBP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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