Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study.

doi:10.1161/JAHA.115.003003

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Article

Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study.

Journal of the American Heart Association - 29 Mar 2016

Lee Tsong-Hai, Ko Tai-Ming, Chen Chien-Hsiun, Lee Ming-Ta Michael, Chang Yeu-Jhy, Chang Chien-Hung, Huang Kuo-Lun, Chang Ting-Yu, Lee Jiann-Der, Chang Ku-Chou, Yang Jen-Tsung, Wen Ming-Shien, Wang Chao-Yung, Chen Ying-Ting, Hsieh Chia-San, Chou Shu-Yu, Liu Yi-Min, Chen Hui-Wen, Liao Hung-Ting, Wang Chia-Wen, Chen Shih-Ping, Lu Liang-Suei, Chen Yuan-Tsong, Wu Jer-Yuarn

Abstract excerpt

BACKGROUND: Ischemic stroke is a major cause of death and disability in the world. A major ischemic stroke subtype, large-vessel ischemic stroke (large artery atherosclerosis; LAA), has been shown to have some genetic components in individuals of European ancestry. However, it is not clear whether the genetic predisposition to LAA stroke varies among ethnicities. We sought to identify genetic factors that...

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PMID: 27025970
DOI: 10.1161/JAHA.115.003003
PMCID: PMC4943273

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