Animal inference on human mitochondrial diseases.

Abstract excerpt

Several pathological mutations in the human mitochondrial genome have been characterized based on medical, genetic and biochemical evidence. The observation that the structure and core functions of the mitochondrial genome are conserved from animals to man suggests that the analysis of animal variation may be informative to further characterize, and possibly predict, human pathological variants. We studied the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Databases as Topic
• Share to Evolution, Molecular
• Share to Genetic Predisposition to Disease