Article
The future of stem cells: Should we keep the "stem" and skip the "cells"?
The Journal of thoracic and cardiovascular surgery - 1 Aug 2016
Menasché Philippe
Abstract excerpt
There is accumulating evidence that the cardioprotective effects of stem cells are predominantly mediated by the release of a blend of factors, possibly clustered into extracellular vesicles, which harness endogenous repair pathways. The clinical translation of this concept requires the identification of the cell-secreted signaling biomolecules and an appropriate transfer method. The study by Wei and colleagues...
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