Article
BRAF mutations in conjunctival melanoma: investigation of incidence, clinicopathological features, prognosis and paired premalignant lesions.
Acta ophthalmologica - 1 Aug 2016
Larsen Ann-Cathrine, Dahl Christina, Dahmcke Christina M, Lade-Keller Johanne, Siersma Volkert D, Toft Peter B, Coupland Sarah E, Prause Jan U, Guldberg Per, Heegaard Steffen
Abstract excerpt
PURPOSE: To investigate incidence, clinicopathological features and prognosis of BRAF-mutated conjunctival melanoma in Denmark. Furthermore, to determine BRAF mutations in paired premalignant lesions and evaluate immunohistochemical BRAF V600E oncoprotein detection. METHODS: Data from 139 patients with conjunctival melanoma (1960-2012) were collected. Archived conjunctival melanoma samples and premalignant...
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