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Article

Inheritance of Chiari-Like Malformation: Can a Mixed Breeding Reduce the Risk of Syringomyelia?

PloS one - 1 Jan 2016

Knowler Susan P, v/d Berg Henny, McFadyen Angus, La Ragione Roberto M, Rusbridge Clare

Abstract excerpt

Canine Chiari-like malformation (CM) is a complex abnormality of the skull and craniocervical junction associated with miniaturization and brachycephaly which can result in the spinal cord disease syringomyelia (SM). This study investigated the inheritance of CM in a Griffon Bruxellois (GB) family and feasibility of crossbreeding a brachycephalic CM affected GB with a mesaticephalic normal Australian terrier and...

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Identifiers

PMID: 27008271
DOI: 10.1371/journal.pone.0151280
PMCID: PMC4805231

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