Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.

doi:10.1038/ng.3529

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Article

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.

Nature genetics - 1 May 2016

Robinson Elise B, St Pourcain Beate, Anttila Verneri, Kosmicki Jack A, Bulik-Sullivan Brendan, Grove Jakob, Maller Julian, Samocha Kaitlin E, Sanders Stephan J, Ripke Stephan, Martin Joanna, Hollegaard Mads V, Werge Thomas, Hougaard David M, Neale Benjamin M, Evans David M, Skuse David, Mortensen Preben Bo, Børglum Anders D, Ronald Angelica, Smith George Davey, Daly Mark J

Abstract excerpt

Almost all genetic risk factors for autism spectrum disorders (ASDs) can be found in the general population, but the effects of this risk are unclear in people not ascertained for neuropsychiatric symptoms. Using several large ASD consortium and population-based resources (total n > 38,000), we find genome-wide genetic links between ASDs and typical variation in social behavior and adaptive functioning. This...

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Identifiers

PMID: 26998691
DOI: 10.1038/ng.3529
PMCID: PMC4986048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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