Article
Dyspoietic changes associated with hepatosplenic T-cell lymphoma are not a manifestation of a myelodysplastic syndrome: analysis of 25 patients.
Human pathology - 1 Apr 2016
Yabe Mariko, Medeiros L Jeffrey, Tang Guilin, Wang Sa A, P Patel Keyur, Routbort Mark, Bhagat Govind, Bueso-Ramos Carlos E, Jorgensen Jeffrey L, Luthra Rajyalakshmi, Chen Weina, Muzzafar Tariq, Kanagal-Shamanna Rashmi, Khoury Joseph D, Daneshbod Yahya, Davanlou Masoud, Li Shaoying, Young Ken H, Miranda Roberto N
Abstract excerpt
Hepatosplenic T-cell lymphoma (HSTCL) is a rare T-cell lymphoma commonly associated with cytopenias. The pathogenesis of cytopenias in patients with HSTCL is not well defined, although the presence of dyspoietic hematopoietic cells and the common association with trisomy 8 raise the possibility of an associated myelodysplastic syndrome (MDS). In 25 bone marrow specimens involved by HSTCL, we systematically...
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