Article
Role of cancer stem cells in racial disparity in colorectal cancer.
Cancer medicine - 1 Jun 2016
Farhana Lulu, Antaki Fadi, Anees Mohammad R, Nangia-Makker Pratima, Judd Stephanie, Hadden Timothy, Levi Edi, Murshed Farhan, Yu Yingjie, Van Buren Eric, Ahmed Kulsoom, Dyson Gregory, Majumdar Adhip P N
Abstract excerpt
Although African-Americans (AAs) have a higher incidence of colorectal cancer (CRC) than White people, the underlying biochemical mechanisms for this increase are poorly understood. The current investigation was undertaken to examine whether differences in self-renewing cancer stem/stem-like cells (CSCs) in the colonic mucosa, whose stemness is regulated by certain microRNAs (miRs), could partly be responsible...
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