Article
C-Kit non-mutated metastatic melanoma showing positive response to Nilotinib.
Dermatology online journal - 15 Jan 2016
Alkeraye S, Dadban A, Lok C, Arnault J P, Chaby G
Abstract excerpt
Melanoma is an aggressive tumor with advanced disease characterized by widespread metastatic lesions and the tumor has traditionally been resistant to most forms of treatment. Indeed, metastatic melanoma has a very poor prognosis with a median survival time of 8-9 months and an estimated 3-year survival rate of less than 15%. Recent advances in our understanding of the genetic profile of melanoma cells and the...
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