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Genome-wide Screening Identifies Phosphotransferase System Permease BepA to Be Involved inEnterococcus faeciumEndocarditis and Biofilm Formation

16 Mar 2016

Abstract excerpt

Enterococcus faecium is a common cause of nosocomial infections, of which infective endocarditis is associated with substantial mortality. In this study, we used a microarray-based transposon mapping (M-TraM) approach to evaluate a rat endocarditis model and identified a gene, originally annotated as "fruA" and renamed "bepA," putatively encoding a carbohydrate phosphotransferase system (PTS) permease (biofilm...

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PMID: 26984142
DOI: 10.1093/infdis/jiw108

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