Article
Role of SKD1 Regulators LIP5 and IST1-LIKE1 in Endosomal Sorting and Plant Development.
Plant physiology - 1 May 2016
Buono Rafael Andrade, Paez-Valencia Julio, Miller Nathan D, Goodman Kaija, Spitzer Christoph, Spalding Edgar P, Otegui Marisa S
Abstract excerpt
SKD1 is a core component of the mechanism that degrades plasma membrane proteins via the Endosomal Sorting Complex Required for Transport (ESCRT) pathway. Its ATPase activity and endosomal recruitment are regulated by the ESCRT components LIP5 and IST1. How LIP5 and IST1 affect ESCRT-mediated endosomal trafficking and development in plants is not known. Here we use Arabidopsis mutants to demonstrate that LIP5...
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