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Article

CD271(+) stromal cells expand in arthritic synovium and exhibit a proinflammatory phenotype.

Arthritis research & therapy - 15 Mar 2016

Del Rey Manuel J, Faré Regina, Usategui Alicia, Cañete Juan D, Bravo Beatriz, Galindo María, Criado Gabriel, Pablos José L

Abstract excerpt

BACKGROUND: CD271(+) stromal cells (SCs) with multipotent stem cell capacity have been identified in synovial tissues, but their functional significance is unknown. We analyzed the distribution of CD271(+) cells in inflammatory synovial tissues as well as their ex vivo immunomodulatory and inflammatory phenotypes. METHODS: CD271 expression was analyzed by immunohistochemistry in synovial tissues and by flow...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26980374
DOI: 10.1186/s13075-016-0966-5
PMCID: PMC4791981

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