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Article

Genetic Diversity of NHE1, Receptor for Subgroup J Avian Leukosis Virus, in Domestic Chicken and Wild Anseriform Species.

PloS one - 1 Jan 2016

Reinišová Markéta, Plachý Jiří, Kučerová Dana, Šenigl Filip, Vinkler Michal, Hejnar Jiří

Abstract excerpt

J subgroup avian leukosis virus (ALV-J) infects domestic chicken, jungle fowl, and turkey and enters the host cell through a receptor encoded by tvj locus and identified as Na+/H+ exchanger 1 (NHE1). The resistance to ALV-J in a great majority of examined galliform species was explained by deletions or substitutions of the critical tryptophan 38 in the first extracellular loop of NHE1, and genetic polymorphisms...

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PMID: 26978658
DOI: 10.1371/journal.pone.0150589
PMCID: PMC4792377

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