Article
Genetic predisposition and hematopoietic malignancies in children: Primary immunodeficiency.
European journal of medical genetics - 1 Dec 2016
van der Werff Ten Bosch Jutte, van den Akker Machiel
Abstract excerpt
It is assumed that patients with some forms of primary immunodeficiency (PID) have a markedly increased risk of cancer as compared to the healthy population. This increased incidence is seen in children as well as adult patients. The type of malignancy depends on the underlying genetic defect, but hematopoietic cancers are most frequent in almost any subtype of PID. In some patients, a malignancy can even be the...
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