Article
Potential Role of Placental Klotho in the Pathogenesis of Preeclampsia.
Cell biochemistry and biophysics - 1 Mar 2016
Cecati Monia, Giannubilo Stefano Raffaele, Saccucci Franca, Sartini Davide, Ciavattini Andrea, Emanuelli Monica, Tranquilli Andrea Luigi
Abstract excerpt
The aim of this study was to analyze the placental expression and allele status of promoter region of Klotho in association with preeclampsia, which represents the most common hypertensive disease of pregnancy. Klotho mRNA and protein levels were determined using real-time PCR and Western blot, respectively, in placental tissue samples obtained from 34 patients affected with preeclampsia and 34 controls. A...
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