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Article

The clinical value of HER-2 overexpression and PIK3CA mutations in the older breast cancer population: a FOCUS study analysis.

Breast cancer research and treatment - 1 Apr 2016

Engels Charla C, Kiderlen Mandy, Bastiaannet Esther, van Eijk Ronald, Mooyaart Antien, Smit Vincent T H B M, de Craen Anton J M, Kuppen Peter J K, Kroep Judith R, van de Velde Cornelis J H, Liefers Gerrit Jan

Abstract excerpt

Studies to confirm the effect of acknowledged prognostic markers in older breast cancer patients are scarce. The aim of this study was to evaluate the prognostic value of HER-2 overexpression and PIK3CA mutations in older breast cancer patients. Female breast cancer patients aged 65 years or older, diagnosed between 1997 and 2004 in a geographical region in The Netherlands, with an invasive, non-metastatic tumour...

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Identifiers

PMID: 26968397
DOI: 10.1007/s10549-016-3734-y
PMCID: PMC4819549

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