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Article

The Effect of Diet and Exercise on Intestinal Integrity and Microbial Diversity in Mice

8 Mar 2016

Abstract excerpt

BACKGROUND: The gut microbiota is now known to play an important role contributing to inflammatory-based chronic diseases. This study examined intestinal integrity/inflammation and the gut microbial communities in sedentary and exercising mice presented with a normal or high-fat diet. METHODS: Thirty-six, 6-week old C57BL/6NTac male mice were fed a normal or high-fat diet for 12-weeks and randomly assigned to...

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PMID: 26954359
DOI: 10.1371/journal.pone.0150502

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