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[Diagnosis and treatment of Lynch syndrome].

Duodecim; laaketieteellinen aikakauskirja - 1 Jan 2016

Seppälä Toni, Pylvänäinen Kirsi, Renkonen-Sinisalo Laura, Böhm Jan, Kuopio Teijo, Järvinen Heikki J, Mecklin Jukka-Pekka

Abstract excerpt

Lynch syndrome (LS) refers to an autosomal dominant genetic predisposition to develop colon cancer or cancers or the uterine corpus, stomach, urinary tract, ovaries, small intestine, mammary gland or bile ducts at a young age. The predisposition to cancer is caused by a germline mutation in one of the genes of the mismatch repair (MMR) system. International recommendations suggest immunohistochemical analysis of...

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PMID: 26951027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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