Article
Investigation of the cause of geographic disparities in IDEXX ELISA sensitivity in serum samples from Mycobacterium bovis-infected cattle.
Scientific reports - 7 Mar 2016
Trost Brett, Stuber Tod, Surujballi Om, Nelson Jeffrey, Robbe-Austerman Suelee, Smith Noel H, Desautels Louis, Tikoo Suresh K, Griebel Philip
Abstract excerpt
Accurately identifying Mycobacterium bovis-infected cattle is critical for bovine tuberculosis prevention and control. One method for identifying infected cattle is an ELISA developed by IDEXX laboratories, which detects antibodies to two M. bovis proteins, MPB70 and MPB83. The assay's sensitivity varies by geographic region, with sensitivities of 77%, 45%, and 9% in bovine serum samples from the United Kingdom...
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