Article
[New Pathogenetic Concepts and Early Pharmacological Studies in Sarcoidosis].
Pneumologie (Stuttgart, Germany) - 1 Apr 2016
Schupp J C, Frye B C, Zissel G, Müller-Quernheim J
Abstract excerpt
The etiology of sarcoidosis is still elusive, yet there has been considerable progress in various areas of basic and clinical research. This review focuses on mechanisms of granuloma formation and on new findings in autoimmunity and genetics of sarcoidosis. A new promising concept arose, where serum amyloid A and/or mycobacterial antigens serve as nidus for granuloma formation. Furthermore, autoimmunity in...
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