Article
The major histocompatibility complex in Old World camelids and low polymorphism of its class II genes.
BMC genomics - 1 Mar 2016
Plasil Martin, Mohandesan Elmira, Fitak Robert R, Musilova Petra, Kubickova Svatava, Burger Pamela A, Horin Petr
Abstract excerpt
BACKGROUND: The Major Histocompatibility Complex (MHC) is a genomic region containing genes with crucial roles in immune responses. MHC class I and class II genes encode antigen-presenting molecules expressed on the cell surface. To counteract the high variability of pathogens, the MHC evolved into a region of considerable heterogeneity in its organization, number and extent of polymorphism. Studies of MHCs in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
