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Mitochondria in lung disease

1 Mar 2016

Abstract excerpt

Mitochondria are a distinguishing feature of eukaryotic cells. Best known for their critical function in energy production via oxidative phosphorylation (OXPHOS), mitochondria are essential for nutrient and oxygen sensing and for the regulation of critical cellular processes, including cell death and inflammation. Such diverse functional roles for organelles that were once thought to be simple may be attributed...

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PMID: 26928034
DOI: 10.1172/jci81113

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