Article
Molecular analysis of the LDLR gene in coronary artery disease patients from the Indian population.
Clinical biochemistry - 1 Jun 2016
ArulJothi K N, Whitthall R A, Futema M, Humphries S E, George Melvin, Elangovan S, Nair Devaki R, Devi A
Abstract excerpt
BACKGROUND: Cardiovascular disease is a leading cause of mortality in Indian population. Mutations in LDLR, APOB and PCSK9 genes may lead to Familial Hypercholesterolemia, an autosomal dominant disorder which in turn leads to cardiovascular diseases. The primary objective of this study is to analyze these genes in CAD patients of Indian population. METHODS: A total of 30 patients were selected out of 300 CAD...
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