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Article

Genetic spectrum of low density lipoprotein receptor gene variations in South Indian population.

Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2018

ArulJothi K N, Suruthi Abirami B, Devi Arikketh

Abstract excerpt

BACKGROUND: Low density lipoprotein receptor (LDLR) is a membrane bound receptor maintaining cholesterol homeostasis along with Apolipoprotein B (APOB), Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) and other genes of lipid metabolism. Any pathogenic variation in these genes alters the function of the receptor and leads to Familial Hypercholesterolemia (FH) and other cardiovascular diseases. OBJECTIVE:...

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Topics

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Share to Apolipoproteins B
Share to APOB gene
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hyperlipoproteinemia Type II

Share to Molecular Epidemiology

Share to Proprotein Convertase 9

Share to Receptors, LDL

Source

Identifiers

PMID: 29269200
DOI: 10.1016/j.cca.2017.12.024

Genes

LDLR
APOB
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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