Article
Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog.
Current biology : CB - 7 Mar 2016
Davison Angus, McDowell Gary S, Holden Jennifer M, Johnson Harriet F, Koutsovoulos Georgios D, Liu M Maureen, Hulpiau Paco, Van Roy Frans, Wade Christopher M, Banerjee Ruby, Yang Fengtang, Chiba Satoshi, Davey John W, Jackson Daniel J, Levin Michael, Blaxter Mark L
Abstract excerpt
While components of the pathway that establishes left-right asymmetry have been identified in diverse animals, from vertebrates to flies, it is striking that the genes involved in the first symmetry-breaking step remain wholly unknown in the most obviously chiral animals, the gastropod snails. Previously, research on snails was used to show that left-right signaling of Nodal, downstream of symmetry breaking, may...
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