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Article

miR-26b inhibits autophagy by targeting ULK2 in prostate cancer cells

24 Feb 2016

Abstract excerpt

Autophagy is a catabolic process widely conserved among eukaryotes that permits the rapid degradation of unwanted proteins and organelles through the lysosomal pathway. The Serine/threonine protein kinase ULK2 (unc-51 like kinase 2) plays an important regulatory role in autophagy thanks to its involvement in mTOR-regulated-initiation and downstream ATG protein-related progression of this catabolic process. An...

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PMID: 26920049
DOI: 10.1016/j.bbrc.2016.02.093

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